SS-31 (Elamipretide)
Protect and restore mitochondrial function at the cellular level.
For research purposes only. These products are not intended to diagnose, treat, cure, or prevent any disease. By purchasing, you confirm these products will be used for legitimate research purposes.
About SS-31 (Elamipretide)
SS-31, also known as Elamipretide, is a mitochondria-targeted tetrapeptide that concentrates in the inner mitochondrial membrane, where it stabilizes cardiolipin and reduces mitochondrial reactive oxygen species. It has reached human Phase 2/3 trials (Barth syndrome, primary mitochondrial myopathy, heart failure), but the pivotal trials — including the Phase 3 MMPOWER-3 — largely did not meet their primary endpoints, and it is not approved. The longevity/anti-aging use is an extrapolation from its mechanism, not a proven human outcome.
Key Benefits
- Targets inner mitochondrial membrane directly
- Stabilizes cardiolipin structure
- Reduces mitochondrial ROS production
- Improves electron transport chain efficiency
Set a goal (top of the page) to see how SS-31 (Elamipretide) scores against it, and what the better-evidenced alternatives are.
Category Ratings
How to Take
Common Side Effects
- Injection site reactions
- Headache
- Mild nausea
- Temporary fatigue
Legal & Regulatory Status
Investigational. Phase 2/3 clinical trials (Barth syndrome, primary mitochondrial myopathy, heart failure) — largely did not meet primary endpoints. Not FDA-approved.
Safety and regulatory details for FDA-approved compounds are drawn from the official product label via openFDA; clinical development status reflects ClinicalTrials.gov. This information is provided for research reference, is not endorsed by the FDA, and may not be complete or current.
Research & Sources
- MMPOWER-3: phase 3 RCT of elamipretide in primary mitochondrial myopathy (PMC10382259)
- Phase 2/3 trial of elamipretide in Barth syndrome (PMC7935714)
Sources are selected for reliability (peer-reviewed literature, openFDA, ClinicalTrials.gov) but this is a research summary, not medical advice, and may not be exhaustive.
Prices at quality-checked sources · as of August 2026 (3 weeks ago)
- 5mg $40.1510mg $74.98
- 10mg $79.99
Observed on each vendor’s public listing — see how these sources are vetted. Peptide Concierge doesn’t sell peptides and isn’t affiliated with any vendor; confirm current pricing at the source.
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