Sermorelin / GHRP-6 Blend
GHRH plus the hungriest secretagogue — deliberate if weight gain is the goal.
For research purposes only. These products are not intended to diagnose, treat, cure, or prevent any disease. By purchasing, you confirm these products will be used for legitimate research purposes.
About Sermorelin / GHRP-6 Blend
A 10mg vial split 5mg sermorelin and 5mg GHRP-6. This is a mechanistically coherent pairing — GHRP-6's GH response actually depends on intact endogenous GHRH signalling, so adding a GHRH analogue addresses its main weakness directly. It is also the most appetite-stimulating blend in the catalog. GHRP-6 activates the hypothalamic NPY/AgRP neurons that drive hunger, and the effect is considerably stronger than with GHRP-2 or Ipamorelin. That makes this blend a reasonable choice if weight gain is the objective and a poor one otherwise, and the fixed 1:1 ratio gives no room to moderate it. A controlled human study also found GHRP-6 increased slow-wave sleep alongside GH, ACTH, and cortisol. No study has examined the combination.
Key Benefits
- Directly addresses GHRP-6's dependence on endogenous GHRH
- Strong appetite stimulation — useful where weight gain is wanted
- Increased slow-wave sleep observed with GHRP-6 in a human study
- Both components clear quickly, so one schedule suits both
Set a goal (top of the page) to see how Sermorelin / GHRP-6 Blend scores against it, and what the better-evidenced alternatives are.
Category Ratings
How to Take
Common Side Effects
- Pronounced hunger — the strongest appetite effect of any blend here
- Water retention
- Transient cortisol and prolactin elevation
- Tingling or numbness in hands
- Lethargy after dosing
- Fixed ratio prevents moderating the GHRP-6 component
Legal & Regulatory Status
Research use only; not FDA-approved. GHRP-6 was never brought to market as a therapeutic. No study exists on the combination. Both components are WADA-prohibited.
Safety and regulatory details for FDA-approved compounds are drawn from the official product label via openFDA; clinical development status reflects ClinicalTrials.gov. This information is provided for research reference, is not endorsed by the FDA, and may not be complete or current.
Research & Sources
- GHRP-6 requires endogenous hypothalamic GHRH for maximal GH stimulation (PMID 9543138)
- GHRP-6 stimulates sleep, GH, ACTH and cortisol release in normal man (PMID 7617137)
- Review: diagnosis of growth hormone deficiency (covers sermorelin/Geref) (PMC6941588)
Sources are selected for reliability (peer-reviewed literature, openFDA, ClinicalTrials.gov) but this is a research summary, not medical advice, and may not be exhaustive.
Prices at quality-checked sources · as of August 2026 (8 days ago)
- 5mg + 5mg (10mg total) $106.64
Observed on each vendor’s public listing — see how these sources are vetted. Peptide Concierge doesn’t sell peptides and isn’t affiliated with any vendor; confirm current pricing at the source.
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