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Skin & Anti-AgingLongevity / General Healthinjectable

NAD+

Cellular coenzyme central to energy metabolism and DNA repair.

Limited evidenceLittle or no published human or animal research. Claims rest on theory, traditional use, or anecdote — treat with particular caution.

For research purposes only. These products are not intended to diagnose, treat, cure, or prevent any disease. By purchasing, you confirm these products will be used for legitimate research purposes.

About NAD+

NAD+ (nicotinamide adenine dinucleotide) is a coenzyme present in every living cell, essential for mitochondrial energy production, sirtuin activity, and DNA repair. Cellular NAD+ declines with age, and direct supplementation is studied for energy, metabolic health, and longevity. Because it is dosed in relatively large amounts, injections are given slowly to minimize flushing and discomfort.

Key Benefits

  • Supports mitochondrial energy production
  • Activates sirtuin longevity pathways
  • Aids cellular DNA repair
  • Studied for metabolic and cognitive vitality

Set a goal (top of the page) to see how NAD+ scores against it, and what the better-evidenced alternatives are.

Category Ratings

Muscle & Strength
N/A
Fat Loss
Minimal
Recovery
Mild
Skin & Anti-Aging
Minimal
Sleep
N/A
Cognitive
Minimal
Immune
Minimal
Longevity
Mild
Bone & Hormonal
N/A

How to Take

Injection

Slow subcutaneous injection; inject gradually to reduce flushing

Common Side Effects

  • Flushing
  • Nausea if injected too quickly
  • Injection site discomfort
  • Lightheadedness

Legal & Regulatory Status

Research use only. Not FDA-approved. IV NAD+ is widely sold but has little controlled human-trial evidence; most published data is for oral precursors (NR/NMN), not IV NAD+.

Safety and regulatory details for FDA-approved compounds are drawn from the official product label via openFDA; clinical development status reflects ClinicalTrials.gov. This information is provided for research reference, is not endorsed by the FDA, and may not be complete or current.

Research & Sources

Limited evidenceLittle or no published human or animal research. Claims rest on theory, traditional use, or anecdote — treat with particular caution.

Sources are selected for reliability (peer-reviewed literature, openFDA, ClinicalTrials.gov) but this is a research summary, not medical advice, and may not be exhaustive.

NAD+

Prices at quality-checked sources · as of August 2026 (3 weeks ago)

Observed on each vendor’s public listing — see how these sources are vetted. Peptide Concierge doesn’t sell peptides and isn’t affiliated with any vendor; confirm current pricing at the source.

CategoryLongevity
Formsinjectable

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