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Skin & Anti-AgingLongevity / General Healthinjectable

Melanotan II

Stimulate melanin production for skin pigmentation research.

Human clinical evidenceStudied in one or more human clinical trials, but not FDA-approved for this use. Evidence quality and trial size vary — see sources.

For research purposes only. These products are not intended to diagnose, treat, cure, or prevent any disease. By purchasing, you confirm these products will be used for legitimate research purposes.

About Melanotan II

Melanotan II is a synthetic analogue of alpha-melanocyte-stimulating hormone (α-MSH) that activates melanocortin receptors and reliably stimulates melanogenesis (skin darkening). Human data is limited to very small pilot studies (pigmentation and erectile function); it is not approved anywhere and carries real safety concerns, including darkening/change of existing moles, nausea, and case reports linking it to melanoma and rhabdomyolysis. Much of what is sold is unregulated.

Key Benefits

  • Reliably stimulates melanogenesis via melanocortin receptors
  • Small human pilot data for pigmentation and erectile function
  • Serious safety concerns — mole changes, melanoma case reports
  • Not approved anywhere; supply is largely unregulated

Set a goal (top of the page) to see how Melanotan II scores against it, and what the better-evidenced alternatives are.

Category Ratings

Muscle & Strength
N/A
Fat Loss
Minimal
Recovery
N/A
Skin & Anti-Aging
Good
Sleep
N/A
Cognitive
N/A
Immune
N/A
Longevity
N/A
Bone & Hormonal
N/A

How to Take

Injection

Subcutaneous injection into abdominal fat, preferably in the evening

Common Side Effects

  • Nausea
  • Facial flushing
  • Fatigue
  • Darkening of existing moles
  • Appetite suppression
  • Increased libido

Legal & Regulatory Status

Research use only. Not FDA-approved anywhere. Associated with safety concerns (mole changes, melanoma case reports). Banned by WADA in competitive sports.

Safety and regulatory details for FDA-approved compounds are drawn from the official product label via openFDA; clinical development status reflects ClinicalTrials.gov. This information is provided for research reference, is not endorsed by the FDA, and may not be complete or current.

Research & Sources

Human clinical evidenceStudied in one or more human clinical trials, but not FDA-approved for this use. Evidence quality and trial size vary — see sources.

Sources are selected for reliability (peer-reviewed literature, openFDA, ClinicalTrials.gov) but this is a research summary, not medical advice, and may not be exhaustive.

Melanotan II

Prices at quality-checked sources · as of August 2026 (3 weeks ago)

Observed on each vendor’s public listing — see how these sources are vetted. Peptide Concierge doesn’t sell peptides and isn’t affiliated with any vendor; confirm current pricing at the source.

CategorySkin
Formsinjectable

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