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KPV

Calm inflammation in skin and gut tissue.

Preclinical evidenceEvidence comes from cell-culture and/or animal studies only. Effects have not been demonstrated in humans.

For research purposes only. These products are not intended to diagnose, treat, cure, or prevent any disease. By purchasing, you confirm these products will be used for legitimate research purposes.

About KPV

KPV is an anti-inflammatory tripeptide derived from the C-terminal end of alpha-melanocyte-stimulating hormone (alpha-MSH). It retains the potent anti-inflammatory properties of alpha-MSH without melanogenic (tanning) effects. Research demonstrates its ability to inhibit NF-kB and reduce pro-inflammatory cytokines in skin, gut, and mucosal tissues.

Key Benefits

  • Potent anti-inflammatory without melanogenic effects
  • Supports skin barrier function
  • Calms gut mucosal inflammation
  • Inhibits NF-kB inflammatory pathway

Set a goal (top of the page) to see how KPV scores against it, and what the better-evidenced alternatives are.

Category Ratings

Muscle & Strength
N/A
Fat Loss
N/A
Recovery
Mild
Skin & Anti-Aging
Mild
Sleep
N/A
Cognitive
N/A
Immune
Mild
Longevity
Minimal
Bone & Hormonal
N/A

How to Take

Topical / Cream

Apply to affected skin area after cleansing and drying thoroughly

Oral / Capsule

Swallow capsule on an empty stomach, morning or evening

Common Side Effects

  • Mild GI discomfort (oral)
  • Skin tingling (topical)
  • Headache

Legal & Regulatory Status

Research use only. Not FDA-approved. Anti-inflammatory evidence is preclinical (animal/cell); not demonstrated in humans.

Safety and regulatory details for FDA-approved compounds are drawn from the official product label via openFDA; clinical development status reflects ClinicalTrials.gov. This information is provided for research reference, is not endorsed by the FDA, and may not be complete or current.

Research & Sources

Preclinical evidenceEvidence comes from cell-culture and/or animal studies only. Effects have not been demonstrated in humans.

Sources are selected for reliability (peer-reviewed literature, openFDA, ClinicalTrials.gov) but this is a research summary, not medical advice, and may not be exhaustive.

KPV

Prices at quality-checked sources · as of August 2026 (3 weeks ago)

Observed on each vendor’s public listing — see how these sources are vetted. Peptide Concierge doesn’t sell peptides and isn’t affiliated with any vendor; confirm current pricing at the source.

CategorySkin
Formstopical, oral

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