Back to All Peptides

IGF-1 LR3

Long-acting IGF-1 analogue that drives muscle growth and recovery.

Preclinical evidenceEvidence comes from cell-culture and/or animal studies only. Effects have not been demonstrated in humans.

For research purposes only. These products are not intended to diagnose, treat, cure, or prevent any disease. By purchasing, you confirm these products will be used for legitimate research purposes.

About IGF-1 LR3

IGF-1 LR3 (Long R3 Insulin-like Growth Factor-1) is an 83-amino-acid analogue of IGF-1 engineered for a markedly extended half-life by resisting binding proteins that normally deactivate native IGF-1. It promotes muscle protein synthesis, hyperplasia, and nutrient partitioning. It is a potent anabolic research compound and demands careful handling given its systemic growth signaling.

Key Benefits

  • Stimulates muscle protein synthesis
  • Promotes muscle cell hyperplasia
  • Enhances nutrient partitioning
  • Extended half-life versus native IGF-1

Set a goal (top of the page) to see how IGF-1 LR3 scores against it, and what the better-evidenced alternatives are.

Category Ratings

Muscle & Strength
Mild
Fat Loss
Minimal
Recovery
Mild
Skin & Anti-Aging
N/A
Sleep
N/A
Cognitive
N/A
Immune
N/A
Longevity
Minimal
Bone & Hormonal
N/A

How to Take

Injection

Subcutaneous injection, typically post-workout or in the morning

Common Side Effects

  • Hypoglycemia
  • Injection site reactions
  • Joint pain
  • Potential organ growth with prolonged use

Legal & Regulatory Status

Research use only. Not FDA-approved. Used as a laboratory research reagent; its anabolic effects are preclinical (animal/cell) with no human therapeutic trials.

Safety and regulatory details for FDA-approved compounds are drawn from the official product label via openFDA; clinical development status reflects ClinicalTrials.gov. This information is provided for research reference, is not endorsed by the FDA, and may not be complete or current.

Research & Sources

Preclinical evidenceEvidence comes from cell-culture and/or animal studies only. Effects have not been demonstrated in humans.

Sources are selected for reliability (peer-reviewed literature, openFDA, ClinicalTrials.gov) but this is a research summary, not medical advice, and may not be exhaustive.

IGF-1 LR3

Prices at quality-checked sources · as of August 2026 (3 weeks ago)

Observed on each vendor’s public listing — see how these sources are vetted. Peptide Concierge doesn’t sell peptides and isn’t affiliated with any vendor; confirm current pricing at the source.

CategoryMuscle & Strength
Formsinjectable

Builds a working set shared across the stack builder, calculator, scheduler and compare.