GHRP-2 (Pralmorelin)
Ghrelin-receptor agonist approved in Japan as a GH-deficiency diagnostic.
For research purposes only. These products are not intended to diagnose, treat, cure, or prevent any disease. By purchasing, you confirm these products will be used for legitimate research purposes.
About GHRP-2 (Pralmorelin)
GHRP-2, also known as pralmorelin, is a synthetic ghrelin-receptor (GHS-R1a) agonist that triggers a strong pituitary GH pulse. It is the most clinically established peptide in this family: Japan approved it as a diagnostic agent for assessing hypothalamic-pituitary function, and the GHRP-2 stimulation test has been studied as a substitute for the insulin tolerance test in hypopituitarism and for detecting secondary adrenal failure. Like ghrelin itself it also raises appetite — a controlled study in healthy men showed a measurable increase in food intake — and produces a modest, transient rise in ACTH, cortisol, and prolactin alongside GH.
Key Benefits
- Strong, reproducible GH pulse in humans
- Best-validated GHS in this family — an approved diagnostic in Japan
- Less appetite stimulation than GHRP-6 at comparable doses
- Commonly combined with a GHRH analogue for additive GH release
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Category Ratings
How to Take
Common Side Effects
- Increased appetite
- Water retention
- Tingling or numbness in hands
- Transient rise in cortisol and prolactin
- Flushing or head-rush shortly after dosing
Legal & Regulatory Status
Research use only in the US; not FDA-approved. Approved in Japan as pralmorelin, a diagnostic agent for hypothalamic-pituitary function testing — a diagnostic indication, not a treatment. Also a WADA-prohibited substance.
Safety and regulatory details for FDA-approved compounds are drawn from the official product label via openFDA; clinical development status reflects ClinicalTrials.gov. This information is provided for research reference, is not endorsed by the FDA, and may not be complete or current.
Research & Sources
- Pralmorelin (GHRP-2) drug profile and development status (PMID 15230633)
- GHRP-2, like ghrelin, increases food intake in healthy men (PMC2824650)
- Clinical usefulness of the GHRP-2 test for hypothalamic-pituitary disorder (PMC9249372)
- GHRP-2 test as a substitute for the insulin tolerance test in hypopituitarism (PMID 18493103)
Sources are selected for reliability (peer-reviewed literature, openFDA, ClinicalTrials.gov) but this is a research summary, not medical advice, and may not be exhaustive.
Prices at quality-checked sources · as of August 2026 (8 days ago)
- 10mg $92.28
Observed on each vendor’s public listing — see how these sources are vetted. Peptide Concierge doesn’t sell peptides and isn’t affiliated with any vendor; confirm current pricing at the source.
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