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FOXO4-DRI

Senolytic peptide that targets and clears senescent cells.

Preclinical evidenceEvidence comes from cell-culture and/or animal studies only. Effects have not been demonstrated in humans.

For research purposes only. These products are not intended to diagnose, treat, cure, or prevent any disease. By purchasing, you confirm these products will be used for legitimate research purposes.

About FOXO4-DRI

FOXO4-DRI is a synthetic peptide designed to disrupt the FOXO4-p53 interaction that keeps senescent ('zombie') cells alive. By releasing p53, it selectively pushes senescent cells toward apoptosis while sparing healthy cells. It is an experimental longevity research compound studied for clearing accumulated senescent-cell burden.

Key Benefits

  • Selectively targets senescent cells
  • Disrupts the FOXO4-p53 interaction
  • Studied for senescent-cell clearance
  • Short, cyclical protocol

Set a goal (top of the page) to see how FOXO4-DRI scores against it, and what the better-evidenced alternatives are.

Category Ratings

Muscle & Strength
N/A
Fat Loss
N/A
Recovery
Minimal
Skin & Anti-Aging
Minimal
Sleep
N/A
Cognitive
N/A
Immune
Minimal
Longevity
Mild
Bone & Hormonal
N/A

How to Take

Injection

Subcutaneous injection in the morning

Common Side Effects

  • Injection site reactions
  • Fatigue
  • Flu-like symptoms during clearance

Legal & Regulatory Status

Research use only. Experimental; not FDA-approved. Senolytic effects are preclinical (cell + mouse) only — no human data.

Safety and regulatory details for FDA-approved compounds are drawn from the official product label via openFDA; clinical development status reflects ClinicalTrials.gov. This information is provided for research reference, is not endorsed by the FDA, and may not be complete or current.

Research & Sources

Preclinical evidenceEvidence comes from cell-culture and/or animal studies only. Effects have not been demonstrated in humans.

Sources are selected for reliability (peer-reviewed literature, openFDA, ClinicalTrials.gov) but this is a research summary, not medical advice, and may not be exhaustive.

FOXO4-DRI

Prices at quality-checked sources · as of July 2026 (3 weeks ago)

Observed on each vendor’s public listing — see how these sources are vetted. Peptide Concierge doesn’t sell peptides and isn’t affiliated with any vendor; confirm current pricing at the source.

CategoryLongevity
Formsinjectable

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