ARA-290 (Cibinetide)
Non-erythropoietic EPO derivative targeting neuropathic pain and repair.
For research purposes only. These products are not intended to diagnose, treat, cure, or prevent any disease. By purchasing, you confirm these products will be used for legitimate research purposes.
About ARA-290 (Cibinetide)
ARA-290 (Cibinetide) is an 11-amino-acid peptide derived from the tertiary structure of erythropoietin that activates the innate repair receptor without EPO's effects on red blood cell production. Research focuses on reducing neuropathic pain and inflammation and promoting tissue repair, particularly in conditions such as sarcoidosis-associated small-fiber neuropathy.
Key Benefits
- Targets the innate repair receptor
- Reduces neuropathic pain
- Modulates inflammation
- No effect on red blood cell production
Set a goal (top of the page) to see how ARA-290 (Cibinetide) scores against it, and what the better-evidenced alternatives are.
Category Ratings
How to Take
Common Side Effects
- Injection site reactions
- Mild headache
- Fatigue
Legal & Regulatory Status
Investigational — studied in Phase 2 trials (as cibinetide/ARA-290) for neuropathic pain and sarcoidosis. Not FDA-approved.
Safety and regulatory details for FDA-approved compounds are drawn from the official product label via openFDA; clinical development status reflects ClinicalTrials.gov. This information is provided for research reference, is not endorsed by the FDA, and may not be complete or current.
Research & Sources
- Phase 2 RCT: ARA-290 (cibinetide) for small-fiber neuropathy in sarcoidosis (PMID 23168581)
- ARA-290 improves symptoms & corneal nerve-fiber density in sarcoidosis (PMID 24136731)
Sources are selected for reliability (peer-reviewed literature, openFDA, ClinicalTrials.gov) but this is a research summary, not medical advice, and may not be exhaustive.
